Most Common Side Effects Are Manageable
The most common adverse reactions that occurred in controlled clinical trials in at least 5% of patients treated with bupropion HCl sustained-release (300 and 400 mg per day) and at a rate at least twice the placebo rate were1:
- Dry mouth
- Nausea
- Insomnia
- Dizziness
- Pharyngitis
- Abdominal pain
- Agitation
- Anxiety
- Tremor
- Palpitation
- Sweating
- Tinnitus
- Myalgia
- Anorexia
- Urinary frequency
- Rash
WELLBUTRIN bioequivalence has been established across immediate-, sustained-, and extended-release formulations.1
The American Psychiatric Association practice guidelines state that anticipated side effects are a key factor in choosing the optimal antidepressant therapy for each patient.3